• Treatment of hypersudationBotulinum toxin injection reduces the amount of sweat produced by around a third over a period of 4 to 8 months.
• Eliminates body odour: By blocking the production of sweat, botox prevents the proliferation of bacteria that cause unpleasant body odour, particularly in the armpits.

For greater comfort, the doctor applies an anaesthetic cream 45 minutes before the treatment. He will then grid the area and perform several superficial injections using very fine needles.

The effects on perspiration start to be felt after 4 to 10 days and last between 6 and 8 months.

Botulinum toxin injections block the nervous message that triggers sweat production in the sweat glands. This does not induce the transfer of perspiration to other areas of the body.

PBSerum® HA is the only recombinant enzyme system in the world specifically developed for remodelling facial and body tissues. Manufactured by Proteos Biotech to strict pharmaceutical standards (ISO 22716 and ISO 13485 certification), it combines three recombinant enzymes (collagenase, lyase and lipase) with high-molecular-weight, non-cross-linked native hyaluronic acid.

Unlike traditional fillers, which add volume without acting on the underlying structure, PBSerum® targets the extracellular matrix, the skin's true support architecture. It eliminates damaged collagen fibres, reduces localised adipocytes, improves tissue permeability and circulation, and thus boosts the natural production of functional collagen. This is what is known as bioremodeling: an in-depth restructuring of the tissue.

This injectable facial reshaping treatment is available in Forever Institut's three clinics at Geneva, Lausanne and Nyon, performed by doctors specialising in aesthetic medicine.

Reshaping and firming the face

PBSerum® is particularly indicated for treating slight sagging of the oval of the face (the “jowls”) thanks to its dual action on skin firmness and the reduction of localised fatty deposits. It improves the overall quality of facial skin, making it more supple, radiant and toned.

• Slight sagging of the oval of the face and loss of contour definition
• Double chin or accumulation of fat under the chin
• Overall improvement in the quality of facial skin

Body treatments

Enzymatic remodelling can also be applied to the body to treat areas that are often resistant to conventional approaches:

• Resistant cellulite (all types and degrees)
• Localised fat (abdomen, thighs, arms, back, inner thighs)
• Skin irregularities secondary to liposuction
• Water retention and chronic oedema

Scars and fibrosis

• Hypertrophic scars and keloids
• Post-surgical fibrosis
• Deep acne scars

Who can benefit from this treatment?

PBSerum® is designed for women and men who want to improve the quality of their skin and reshape their figure without surgery. A medical consultation A preliminary consultation in one of our clinics in Geneva, Lausanne or Nyon is essential to assess whether the treatment is suitable for your profile and to define the optimum protocol.

The power of PBSerum® lies in the synergy of three highly purified recombinant enzymes produced by genetic engineering (recombinant DNA technology). This manufacturing process guarantees maximum purity, perfect reproducibility and superior safety compared with enzymes of animal origin.

Collagenase G&H PB220: skin firming

Collagenase selectively eliminates non-functional, altered or disorganised collagen fibres, those damaged by the sun, tobacco or ageing, and stimulates the synthesis of new collagen.

Lipase PB500: reduction of localised fat deposits

Lipase breaks down triglycerides inside adipocytes, reducing their volume without destroying the cells or upsetting the hormonal balance. The fatty acids released are naturally metabolised by the body. This mechanism enables precise, natural remodelling of the areas treated - double chin, abdomen, arms - without surgery.

Lyase PB72K: improves circulation and reduces cellulite

Lyase breaks down the polysaccharides responsible for water retention and improves tissue permeability. It promotes lymphatic drainage, optimises the diffusion of other active ingredients and reduces the orange peel appearance characteristic of cellulite. The skin is smoother and more supple to the touch.

High molecular weight hyaluronic acid (HMW-HA)

Combined with the enzymatic system, non-cross-linked native hyaluronic acid plays an anti-inflammatory role, improves tissue cohesion and hydration, and reduces fibrotic markers. It acts as a biological vector to optimise and prolong the action of the enzymes.

Progressive, natural results

The first effects of remodelling with PBSerum® can be seen after several days, or even 3-4 weeks. The results then gradually improve as the tissue is restructured and new collagen is formed. In some cases, one session is enough; however, it is advisable to complete the entire protocol. Full results can be seen 4 to 6 weeks after the last session.

Recommended number of sessions

The protocol is adapted to each indication and determined during the initial consultation. Forever Institut doctors recommend :

• Facial reshaping (sagging / adiposity): 3 sessions spaced 4 weeks apart
• Cellulite: 3 sessions, 2 weeks apart
• Fibrosis and scars: 3 sessions spaced 3 weeks apart
• Localised fat: 2 to 3 sessions, 2 weeks apart

Long-term benefits

In addition to visible results, PBSerum® improves the structural quality of skin tissue over the long term. By restoring the architecture of the extracellular matrix and stimulating collagen neosynthesis, it ideally prepares the skin for other aesthetic treatments (hyaluronic acid injections, laser), optimising and prolonging their effects.

A safe, scientifically validated treatment

Proteos Biotech, creator of PBSerum®, has over 10 years' experience in the research and development of recombinant enzymes for dermatology and aesthetic medicine. 

Possible side effects

Side effects are generally minor and transient:

• Slight redness or swelling at the injection site (resolving within a few hours)
• Slight bruising may occur
• Slight local sensitivity in the 24 to 48 hours following the session

Contraindications

In certain situations, treatment should be postponed or avoided:

• Pregnancy and breastfeeding
• Active skin infection at the injection site
• General infectious state (bacterial or viral)
• Non-stabilised or active autoimmune disease
• Anticoagulant treatment (temporary cessation necessary on medical advice)
• Known hypersensitivity to one of the ingredients (hyaluronic acid, enzymes)
• Known allergy to insect bites (possible reactivity with hyaluronidase)

Precautions to be taken

Before treatment : avoid any aggressive products (retinoids, exfoliating acids) a few days before the session.

After treatment : avoid sources of intense heat, strenuous sporting activity for 24 to 48 hours and any cosmetic treatment for 3 to 4 days.

Forever Institut has been a leading centre for aesthetic medicine in French-speaking Switzerland since 1997. Founded by Dr Luigi L. Polla, With over 25 years of expertise in injectable treatments and advanced technologies, we can offer you :

• Doctors specialising in aesthetic medicine, trained in the latest bioremodelling techniques
• Personalised support from initial assessment to final results
• Three accessible clinics in Geneva, Nyon and Lausanne
• An approach based on science: natural results, respect for physiology
• A range of complementary treatments for optimal, long-lasting results.

Botulinum toxin type A is a protein naturally produced by the bacterium Clostridium botulinum. In aesthetic medicine, its injection causes a temporary relaxation of the targeted muscles, visibly reducing expression lines.

The treatment is recognised and approved for glabellar wrinkles (frown lines), crow's feet, forehead wrinkles, platysma (neck wrinkles) and hyperhidrosis (excess perspiration). At Forever Institut, aesthetic doctors use products that are recognised and selected for their effectiveness and safety, according to each patient's profile.

With 30 years' expertise in aesthetic medicine in French-speaking Switzerland, Forever Institut applies a rigorous medical approach to botulinum injections: each treatment is preceded by a detailed morphological analysis and tailored to the specific facial features of each patient.

Botulinum toxin is injected into the upper third of the face, where repeated muscular contractions of the muscles responsible for facial expressions end up creating permanent furrows. Three areas are treated in current practice:

Lion's wrinkles (glabella)

Vertical wrinkles between the eyebrows, linked to the corrugator and procerus muscles. Botulinum toxin injection for frown lines is the oldest clinically validated area - it is often the entry point for first-time patients.

Forehead wrinkles

Horizontal wrinkles that appear when the eyebrows are raised. At Forever Institut, we understand that muscular forces and movements are synergistic. So, to ensure a harmonious result, forehead wrinkles are considered to be «3 zones» because their treatment almost always includes the glabella and crow's feet.

Crow's feet (lateral canthal wrinkles)

Fan-shaped wrinkles that start at the outer corner of the eyes when smiling. Botulinum toxin injection for eye wrinkles is particularly appreciated for its natural result and discreet rejuvenating effect.

Forever Institut's doctors generally recommend the 3-zone treatment to obtain a harmonious result over the entire upper third of the face. The dosage and injection points are adapted to the anatomy, muscle tone and individual objectives of each patient.

Platysma (neck wrinkles)

Botulinum toxin can also be used to treat vertical neck wrinkles linked to the platysma muscle, often called «platysmal bands». Over time, this muscle becomes more visible and contributes to the appearance of a slack, marked neck. Botulinum toxin injections relax these muscle contractions, softening the vertical cords of the neck and redefining the oval of the face. The treatment offers a natural rejuvenating effect, with a visibly smoother, tighter neck and a better-defined jawline. Results appear gradually over a few days and generally last 3 to 4 months. 

The first effects of botulinum injections appear between the 5th and 7th day following treatment. The final results are visible between the 10th and 15th day. The effectiveness of the treatment is maintained for an average of 3 to 5 months, depending on the patient. Clinical trials document an average duration of around 3 months, but the effect often lasts slightly longer.

With repeated sessions, the targeted muscles gradually develop the habit of contracting less, which tends to prolong the interval between treatments. Forever Institut recommends around 3 sessions a year to maintain the benefits of the treatment.

One notable advantage: botulinum toxin injections also act preventively, limiting the worsening of expression lines before they crystallise in the tissues with age.

Before the session

To minimise the risk of bruising, avoid taking anti-inflammatory drugs, aspirin and blood-thinning supplements (omega-3, turmeric, vitamin C) in the days leading up to your appointment. If you are taking anticoagulants, tell your doctor.

After the session

• Avoid compressing (helmet, headband...) or massaging the injected area for 48 to 72 hours.
• Avoid saunas, steam baths and strenuous sports during the hours following treatment.
• Contact Forever Institut if skin reactions persist beyond 24 hours.

Contraindications

• Pregnancy and breastfeeding
• Allergy or hypersensitivity to botulinum toxin type A
• Infection or inflammation of the skin near the injection site
• Muscle disorders or neurological disease (myasthenia gravis, Lambert-Eaton syndrome, ALS)

Possible side effects

Undesirable effects are generally transient and not serious: localised redness or papules (disappearing in less than an hour), bruising (resolved within a week), headaches in the hours or days following the injection, a feeling of heaviness or slight asymmetry during the stabilisation period (2 weeks). These effects are not systematic and vary from one patient to another. In the event of asymmetry, a correction can be made at the follow-up appointment.

Forever Institut has been a leading medical aesthetic centre in French-speaking Switzerland since 1997. Founded by internationally renowned dermatologist Dr Luigi L. Polla, Forever Institut boasts a team of experienced aesthetic doctors.

Forever Institut's approach is based on three principles: medical precision, natural results and personalised support. The 15-20 day check-up is free of charge, and bears witness to this commitment to quality. With clinics in Geneva, Nyon and Lausanne, French-speaking Switzerland has easy access to Forever Institut's recognised expertise.

L’injection de lèvres à l’acide hyaluronique est un traitement médical esthétique consistant à injecter un gel de remplissage à base d’acide hyaluronique (AH) dans les tissus des lèvres et/ou leur contour. L’acide hyaluronique est une molécule naturellement présente dans l’organisme, dont la propriété hydrophile lui permet d’attirer et de retenir l’eau : il apporte ainsi volume, hydratation et définition aux lèvres.

Ce type d’injection permet de traiter plusieurs problématiques : lèvres fines ou asymétriques, perte de volume liée au vieillissement cutané, muqueuses déshydratées, rides péri-labiales (dites « rides de code-barres ») et manque de définition du vermillon ou de l’arc de Cupidon.

Chez Forever Institut, les injections lèvres sont pratiquées depuis 1997 par des médecins spécialisés en médecine esthétique à Genève, Nyon et Lausanne. Chaque traitement est personnalisé selon le type d’acide hyaluronique sélectionné (fluide pour l’hydratation, plus dense pour le volume) et les objectifs propres à chaque patiente et patient.

Volume et repulpage

The hyaluronic acid injections permettent d’augmenter le volume des lèvres tout en respectant l’harmonie naturelle du visage, le dessin du vermillon et l’arc de Cupidon. Le résultat peut être aussi naturel ou aussi affirmé que vous le souhaitez.

Deep hydration

Une formule d’AH plus fluide peut être sélectionnée pour apporter une hydratation intense aux muqueuses sans nécessairement ajouter de volume. Les lèvres paraissent plus lisses, plus fraîches et légèrement repulpées, sans les petites peaux sèches ni les sillons disgracieux.

Redéfinition du contour (rides de code-barres)

L’injection d’acide hyaluronique sur le pourtour des lèvres traite efficacement les rides péri-labiales, souvent accentuées par le tabagisme, les mimiques et le vieillissement. Autre avantage : le rouge à lèvres ne bave plus dans ces petits sillons.

Profiloplastie et équilibre facial

Les injections lèvres s’inscrivent dans une approche de profiloplastie : elles aident à équilibrer les proportions du visage et à créer une harmonie entre ses différents éléments, en corrigeant des lèvres trop fines ou asymétriques.

Les effets d’un traitement à l’acide hyaluronique sont généralement visibles dès l’injection. Pour apprécier pleinement les résultats définitifs, les médecins de Forever Institut recommandent d’attendre 2 à 4 semaines que l’œdème se résorbe complètement.

Les résultats durent en moyenne 6 à 12 mois selon le type d’AH utilisé, le métabolisme et le mode de vie de chaque patient. Chaque traitement inclut un rendez-vous de contrôle et retouches à 2 semaines.

Pionniers de la médecine esthétique en Suisse romande depuis 1997, les médecins de Forever Institut pratiquent les injections de lèvres à l’acide hyaluronique avec une approche médicale rigoureuse et un sens aigu de l’esthétique naturelle. Chaque injection est un acte médical réalisé après consultation personnalisée, jamais un geste standardisé.

• 30 ans d’expertise en injections esthétiques à Geneva, Nyon and Lausanne
• Médecins formés aux dernières techniques d’injection (canule et aiguille)
• Produits d’acide hyaluronique sélectionnés pour leur qualité et leur biocompatibilité
• Rendez-vous de contrôle inclus à 2 semaines
• Résultats naturels, proportionnés, pensés pour chaque visage

• Filling in wrinkles: Some wrinkles look good on us; they are positive and reflect the great experiences of our lives. Others make us look sad, tired or angry. Injections of dermal fillers can restore volume to our face and soften its features.
• Restore volumes : Hyaluronic acid is essential for restoring the skin's youthful volumes, smoothing its surface and reinforcing its firmness. It is also effective in redefining the oval of the face, and can be injected into the cheekbones for an attractive lifting effect.
• Profiloplasty Hyaluronic acid injections can be used to work on the overall harmony of a profile (nose, chin). It can correct a receding chin or lips that are too thin in relation to the rest of the face.
• Moisturising and stimulating collagen : it acts like a real sponge, retaining water in the tissues and ensuring optimal hydration of the skin, giving it a younger, more radiant appearance.

  Over time, it stimulates collagen production in the skin, helping to improve its firmness and natural elasticity.

After an in-depth discussion with your doctor, he or she will choose the type of hyaluronic acid best suited to your needs and inject the area to be treated using a cannula or needle, after disinfecting the area.

For greater comfort during the treatment, an anaesthetic cream can be applied to the area concerned.

The effects of HA treatment are generally visible as soon as the injection is given, but to fully appreciate the final results, it is necessary to wait 2 to 4 weeks before the swelling subsides and the product settles into place.

It is essential to know that a syringe of hyaluronic acid contains 1 ml, equivalent to one teaspoon, which is insufficient to fully restore facial volumes.

To meet your specific needs and make it easier for you to achieve the results you want, we propose degressive rates on hyaluronic acid syringes used during the same session (with the exception of injections for the forehead, lips and the nose).

• Very natural effect and biocompatibilityHarmonyCa® is made from a substance naturally present in the body, making it a highly biocompatible product. Because it stimulates the body's own production of collagen and elastin, the effect is very natural.
• Restores firmness HarmonyCa® is used in cases of loss of skin elasticity, wrinkles or visual sagging of the face.
• Light filling HarmonyCa®: Thanks to the hyaluronic acid it contains, HarmonyCa® can be used to make up for slight loss of volume, particularly in the cheeks.

After cleansing and removing make-up, the doctor injects HarmonyCa® under the dermis. The injection is not very painful because the product contains lidocaine, a local anaesthetic.

Thanks to the hyaluronic acid contained in HarmonyCa®, the lifting and volumising effect is immediate and lasts for several months.

The production of neocollagenase (production of new collagen fibres) occurs over time thanks to calcium hydroxyapatite (CaHA). This firming effect generally lasts from 12 to 18 months.

• Prolonged biostimulationThe gel preserves the growth factors, which will be released over a long period of time, stimulating the skin (biostimulation).
• Reduces fine lines: the growth factors present in the platelets accelerate collagen synthesis, revascularisation and tissue repair. This treatment therefore achieves an overall rejuvenating effect on dark circles.
• Improves skin firmnessThe growth factors present in the platelets will restore elasticity and suppleness to the skin.
• Improvement of dark circles FRP gel improves the quality of the skin around dark circles, lightens them slightly and partially fills in the hollow. It gives your eyes a fresher look.

The PRF gel is prepared from your own blood. A small quantity of blood is taken during a blood test, which is then centrifuged, part of which is heated to make the gel. The other part, the PRF containing the growth factors, will be mixed with it - resulting in the "PRF gel", which will be reinjected into the dark circles.

They improve the overall quality of the dermis: radiance, density, firmness and elasticity. PRF and EZ Gel reduce fine lines, restore volume, lighten dark circles and help tissue repair. They can also help to improve certain hyperpigmentation or light scars. As with other biostimulation treatments, you need to have reasonable expectations and patience to see how effective the treatment is over time.

They optimise the skin's natural potential, encouraging regeneration rather than correction. The treatment is safe, with no risk of allergy or over-correction, and can often be suitable even for those who cannot benefit from other techniques.

PRF and EZ Gel are particularly good for the delicate area around the eyes. I like to combine the two treatments in several layers for optimum regenerative action. They can also be used all over the face, and even on the scalp and hands.

Both. For young skin, it's an excellent preventive treatment that maintains skin quality and revives radiance. For more mature skin, it stimulates the repair and collagen production processes.

• Brightens the complexion: By encouraging cell renewal, it evens out the complexion for a more luminous result. Skin looks younger, more radiant and better hydrated.
• Improves skin texture: with a series of sessions, it refines skin texture and smoothes out skin irregularities such as dilated pores, dark circles and acne scars
• Boosts collagen production: By creating tiny, controlled lesions, microneedling triggers a powerful skin regeneration mechanism. It boosts the production of collagen and elastin, the fibres essential for skin firmness and elasticity.
• Moisturises and plumps the skin: the growth factors present in the platelets will deeply moisturise the skin, restoring its elasticity and suppleness.

• Improved skin quality : polynucleotides are powerful cell regenerators, improving the overall quality of the skin.
• Smoothes fine lines and improves elasticityPolynucleotides act as bio-stimulators and improve skin hydration, texture and elasticity, helping to treat superficial lines and wrinkles.
• Reveals a radiant complexionThe cocktail of bio-stimulating vitamins contributes to a brighter, more radiant complexion.
• Tightening of poresThey help to reduce the size of pores, giving the skin a more elastic and healthy appearance.
• Reducing acne scarsThey have a regenerating effect, repairing damaged cells and helping to reduce acne scars and other skin imperfections.
• Improves the colour of dark circlesThey promote better blood circulation and more even colouring of the under-eye area.

The polynucleotides are injected using micro-needles or very fine cannulas. The session lasts between 30 and 45 minutes. Slight redness or swelling may appear immediately afterwards, but this generally disappears within a few hours.

Post-injection oedema and ecchymosis may appear and last for up to 48 hours, especially in the periorbital region.

Les indications du Radiesse visage et corps

L’injection Radiesse est recommandée dans les situations suivantes :

• Relâchement cutané débutant du visage (pommettes, ovale du visage, sillons naso-géniens)
• Perte de tonicité du cou et du décolleté
• Vieillissement des mains (fonte graisseuse, saillance veineuse)
• Prévention du vieillissement : améliorer la qualité de peau avant l’apparition de signes marqués
• Rides et ridules modérées résistantes aux soins topiques
• Atonie cutanée des bras et des genoux

Treated areas

• Visage : pommettes, ovale, sillons naso-géniens, tempes
• Neck and décolleté
• Hands
• Corps : bras, genoux

Qui peut bénéficier d’une injection Radiesse® ?

Le Radiesse® s’adresse aux hommes et aux femmes qui souhaitent améliorer la qualité et la fermeté de leur peau. Il convient particulièrement aux peaux présentant une perte d’élasticité précoce ou modérée. Une consultation médicale préalable avec un spécialiste de Forever Institut est indispensable pour évaluer votre profil cutané et confirmer l’indication.

Des résultats progressifs et naturels

Les premiers effets du rajeunissement de la peau par Radiesse® apparaissent quelques semaines après l’injection, une fois que la production de collagène et d’élastine est amorcée. La peau regagne en tonicité, en fermeté et en qualité de texture de façon graduelle.

Combien de temps durent les résultats ?

Les résultats d’une injection Radiesse® durent entre 10 et 12 mois. Le produit se dégradant lentement, le protocole recommandé par les médecins de Forever Institut est de 1 à 2 injections la première année, puis 1 injection annuelle en entretien pour maintenir les bénéfices.

Précautions avant l’injection Radiesse®

• Éviter les anti-inflammatoires, l’aspirine et les compléments fluidifiants (oméga-3, curcuma, vitamine C) dans les jours précédant la séance pour limiter le risque d’ecchymoses

Précautions après l’injection Radiesse®

• Éviter piscine, jacuzzi, sauna pendant les 48 heures suivant le traitement (risque infectieux)

Contraindications

• Pregnancy and breastfeeding
• Sensibilité connue aux anesthésiques locaux de type amide (lidocaïne)
• Infection cutanée, plaie ouverte ou maladie cutanée active sur la zone à traiter
• Sinusitis and fever
• Porphyria
• Maladies auto-immunes

Forever Institut has been a leading centre for aesthetic medicine in French-speaking Switzerland since 1997. Fondé par le Dr Luigi L. Polla, l’institut conjugue expertise médicale, rigueur scientifique et sens du résultat naturel.

• Plus de 30 ans d’expertise en injections esthétiques en Suisse romande
• Médecins spécialisés en médecine esthétique, formés aux derniers protocoles d’injection Radiesse®
• Trois cliniques accessibles : Geneva, Nyon and Lausanne
• Protocoles personnalisés, adaptés à chaque morphologie et à chaque âge de la peau
• Approche naturelle : l’objectif n’est jamais de transformer, mais de révéler.